CARNEGIE INSTITUTION OF WASHINGTON DEPARTMENT OF GENETICS COLD SPRING HARBOR, LONG ISLAND, N. Y. February 14, 1950 DR. Joshua Lederberg Department of Genetics University of Wisconsin Madison, Wisconsin Dear Joshua, I think the following compounds, in addition to methyl green, will suit your mysterious purposes: basic fuchsin, mereuric chloride, silver nitrate, sodium hydroxide and sulfuric acid, These are all highly toxic, and clearly nonmutaegenic within the limits of the phege and streptomycin methods of detection. There are lots of others that are nonmutagenic but not very toxic -- I assime you don't care about these, I’m anxious to get your note -- my curiosity is roused, Best regards to Esther -- Sincerely, Evelyn Witkin