July 1, 1948. Dear Miss Kann, At Dr. Luria's request I am sending you the following cultures derived from K-12: Y-10 Threonine, Leucine, Thiamin -- (T-L-B1-) Y-87 Biotin, Methionine -- (B-M-) and Lac1-V1r 58-161 Simply B-K-. These cultures are referred to in detail in my paper in Genetics, 32:505. Luria implied that you might have some new single mutants of K-12. Is this the case? Let me know if you have any difficulty in making "crosses". There should be none. Yours sincerely, Joshua Lederberg Assistant Professor of Genetics.