° THE JOHNS HOPKINS HOSPITAL

BALTIMORE 5. MARYLAND

RICHARD W. TELINDE.M. O.

WALOCK. M.D. RUSSELL H. MORGAN. M D.

PN-IN-CHIER RADIOCLOGIST-IN-CHIEF GYNECOLOGIST-IN-CHIEF

DN J. EASTMAN, M.D. ARNOLD R. RICH. M.D. JOHN GC. WHITEHORN. M. D.

fRICIAN-IN-GHIEF . PATHOLOGIST-IN-CHIEF PSYCHIATRIST-IN-CHIEF

EE HARVEY, M. D. FRANCIS F. SCHWENTKER. M.D. ALAN GC. WOODS. M.D.
PEDIATRIGIAN-IN-CHIEF OPHTHALMOLOGIST-IN-CHIEF

HAN-IN-CHIEF

 

RUSSELL A. NELSON, M. D.. DIRECTOR

27 dune 195)

ear Joshua,

In three days my duties at Hopkins will come to an end, and I shall plunge

linto the lab at Yale. It will be possible to take time to think and enjoy

| : : : :
‘some of these biolosical problems inthe laboratory once azaine

It do not know how matters stand out there now as far as that “copper” organism
‘is concerned. However, until the work is better organized on a gvenetic basis
‘I could as you svgzest oursue the DNA of some of tne yeastse Tf and when yéux
Ihave the time and are still interested. why don't you send a few grams of yeasf
of the type you are working on so that I might begin to work out satisfactory
analysis of the DNA. Of course I am vitally interested in working on the DNA of
the copper bug as soon as is feasible. And I wonder if it ionld not be worthwhile

whether it is mutant or a transformation or what it is. J shail he very

interasted ‘to hear how things are zoing.s As Tom Sourtenay said when i last sav
him, it is not surpirsine to us that troubles have come your way because of cur
own experiences, “shen + first noted the phenomenon everything clicked in every

experiment - including the 15 tube ones. Sw We put the work aside for a while
to work on the new virus nucleotide and we returned to it the next spring Aw?
although we could reproduce everythin eventually, many things we

re very stubborne
‘Thether the oreanisns changed somewhat or whtertpthe new media (ther? was very

rapid turnover of materials in the lab) or what was never clear, Little things
like small changes in the NaCl content of the media threw us off < tes

My address in New “aven will be:

Dr. “awrence L. Weed
Department of Pharmacology __
School of edicine

Yale University

Cedar Street

New Haven, Conne

 

I shall be busy initiating some work on tumors, but it will be interesting to
carry some side projects as the opportunities arise - especially any that :

touch on genetics.
My best to you and thanks for your stimulating letters during the year. I am
sorry [was not able lo answer them more carefully at the times

Sincerely yours,

7
Lawrence Le “eede