UNIVERSITAT BASEL UNIVERSITY OF BASEL INSTITUT FUR HYGIENE UND BAKTERIOLOGIE INSTITUTE FOR HYGIENE AND BACTERIOLOGY BASEL (SWITZERLAND) = March 29 , 1954 PETERSPLATZ 10 Dr. Joshua Lederberg Professor University of Wisconsin Department of Genetics Madison, 6 Dear Doctor Lederberg, I appreciate very much the receipt of three reprints on your most interesting genetic studies on Salmonella and Escherichia. I found with these reprints a typewritten copy on your simple method for isolating individual microbes and underneath a question. My answer would be positively: yes. I-do think that any simple modification of the single cell technique is important in order to help the extension of this essential method. We shall be glad to try out ourselves your technique. | | . . With best greetings Yours very sincerely for Jd. Tomesik