4 UNIVERSITY OF CALIFORNIA
DEPARTMENT OF ZOOLOGY
BERKELEY 4, CALIFORNIA

January 21, 1958

Professor Joshua Lederberg
Department of Genetics

The University of Wisconsin
College of Agriculture
Madison 6, Wisconsin

Dear Joshua:

Of course I am glad that you made the comment in your recent
letter concerning my paper on the scope of genetics, You are cor
rect, and I am grateful for this correction. What I had in mind
when I wrote the article was as I realize now, not work on DNA,
but what I thought was work accomplished on the tobacco mosaic
virus, in crystalline form. I had thought that the various chemical
mutants which were investigated by Knight had been obtained after
treatment "in the test tube", However, a conversation with Knight
clarified the point that this has really not yet been accomplished
to anybody's full satisfaction.

Hope to see you soon, with best wishes,

Sincerely yours,

Cart

Curt Stern

CS/sm