ATOMIC

CABLE ADDRESS ‘* RESEARCH"

IN YOUR REPLY PLEASE QUOTE

 

FILE NO... cece ceccteeee cece neesenerteseeenees

NATIONAL RESEARCH COUNCIL
CANADA

ENERGY PROJECT

CHALK RIVER. ONT.

September 15, 1949.

Dr. Joshua Lederberg,
University of Wisconsin,
College of Agriculture,
Madison 6, Wis.

Dear Joshua,

I am sorry not to have sent the W677/SR
mutant but we have not yet got down to producing one. However
we have some 58-161/SR strains which I am sending under separate
cover, and which mav be of use to you.

Tests for the linkage of SR with the various
sugar loci other than Lac has just been started and is vielding
beautifully anomalous results, of the sort which from your letters
I gather you have already run into.

The streptomycin story should be complete by
Christmas and I would be glad if you cculd have a look at it
before the A.A.A.S. Meetings.

Incidently would you mind if Dr. Klaus Rothfels,
who has been working here during the summer, used your strains for
a genetics laboratory exercise in the course which he gives at the
University of Toronto? He has the pre-med students particularly in
mind. Dr. Rothfels has been working on gamma-induced chromosome
breaks in grasshoppers, but spent a couple of very productive
weeks with the bacteria before leaving. He is quite a sound person
and in any case would not use them for investigational work with-
out your approval,

Sincerely,
ned WA
é

Howard B. Newcombe
HBN:be