wy WY Le SOUTHERN ILLINOIS UNIVERSITY CARBONDALE, ILLINOIS January 18, 195) Dr. Joshua Lederberg Department of Genetics The University of Wisconsin College of Agriculture Madison 6, Wisconsin Dear Josh Jerry has prepared two cultures with clear-cut markers which she has tested for fertility but did not check for the markers. These cultures will copulate and give good asc@ spores. We would, of course, be pleased to receive any additional mtants that may be derived from studying them. It is difficult to give complete directions and it might very well serve Rubbo's purpose better to spend some time down here in getting started, and that would be a good way of transferring the technique directly to your laboratory. We would be happy to accomodate him in this regard, if he is interested. I think it would be very interesting to try out some U.V. treatments followed by matings. We have done nothing like that and I do not know whether the ability to copulate would survive.U.V. treatment. Let me know if Rabbo is interested in coming down here. If funds are not available, I could give him a flat fee of $50 for a lecture. Best regards to you and Esther from beth of us. Director Biological Research Laboratory CCL: gb #15121 a Goa mA WE MG #“l4354H+ SG MA NE MG