January 23, 1956

Dr. BE. F. Jay
National Institutes of Heal th
Bethseda 14, Mc,

Dear Dr. Jay:

I noted with gnterest your communication to Proc Soc on strain variabikity
in response to hypnotics. Cavalli and I are collecting material for a mono-
graph, and wa I would be grateful to you for a reprint of it. Have you

any more recent word on the enzymatic basis of the differences, as hinted at
in the paper?

If you can give ma any lsada to additicnal references on thts general
teric wf pharmecological varlebility, beyond those already cited in your

note, I would be indebted to you. ‘Bo you know, e.g., of any recent work
on the atropine esterase system in rabbits?].

Yours sincerely,

Josma Lederberg