December 15, 1957

Dear Professor Haldane:
ee

My wife and 1 want to extend our tnanks for your generous
hospitslity and forpearance during our visit last month. These
are, of course, eyually directed to Helen and to urs. Mahalanobis.
We were especially sorry that she was relatively voiceless, judging
from the conversations we did seize upon. Ail in ail we did have
a most imtroutive and interesting experience, and we appreciate
very much having had the opportunity.

Cf ccurse, we did not see very mich of "India" owing to the
briefness of our visit, and our profound ignorance and inexperience.
But we had to get over that stage by just such a visit, and hext
time we will know very mich better what to plan to do. The world is
shrinking, and if it survives at all, we know there will be km a next
time. ie hopa there will likewise be an occasion to return your
hospitality.

Do keep a lookout for a book I am sending by sea wail. You had
indicated you hed not had an opportunity to see the Symposium on
the Chemical Basis of Heredity (Johns Hokking U., 1956) and I hope
it will be of some interest and use to you. It is stili very nearly
the last word.

we've been back just long enough how to settle an, and resume
our research programs. For the moment, I'm concentrating on the
inheritance of the 'F' factor, and Esther is amplifying some pre-
liminary axperiments én whether crossing-over in E. coli is
reciprocal.

Thank you for calling my attention to the stachyose story in
Pisum. I will see if there isn't some way to reinvestigate it by
% ‘Hodern mathods'. However, the figures in youb table 10, page 59,
are not terribly envouraging, es they point to incomplete blocks
and indirect effects that would be difficult to attribute to
qualitative failures in any particular enzyme. Which ia not
fer from your own remarks.

Yours sincersly

Joshua Lederberg