DEPARTMENT OF SCIENTIFIC AND INDUSTRIAL RESEARCH

National Collection of Industrial Bacteria
Telephone: Mo .esey 1380

Telegrams : CHEMISTRY, TEDDINGTON CHEMICAL RESEARCH LABORATORY

TEDDINGTON
Any reply to this letter to

be addressed to : MIDDLESEX
THE DIRECTOR

Our Ref: WSG 66/30/7 7th December, 1956.
Your Ref: JL/ nhn

Dear Professor Lederberg,

Thank you for your letter of November 26th, Since then I have written again

to Dr. Hughes, of John and E, Sturg@Ltd,, Selby, Yorkshire, who requested your
Kl12 strain of E. coli. He has now replied:-

"The idea from which I hope to develop a method of gluconic scid determination
was described by SS, Cohen, J, Biol, Chem, 177, 607, (1949), "Adaptive enzyme
formation in the study of uronic acid by the K12 strain of E, coli". The author
observes that 'the most marked diauxie was observed with the K12 strain of Tatum
and Lederberg, (J. Bact, 53, 673, 1947)'.

He then says "It now appears that I shall have to postpone this project for
some time and I think the best arrangement would be for me to obtsin the strain
from Dr, Hayes when it is needed",

Thank you for your help, It is greatly appreciated,

Professor Joshua Lederberg, Yours sincerely,
Depertment of Genetics, ft ys 0
The University of Wisconsin, tA Ss. . KER ASE

College of Agriculture
Madison , Wise, U.S.A, W.S. Greaves,