Lonc IsLAND BIOLOGICAL ASSOCIATION
COLD SPRING HARBOR, LONG ISLAND

THE BIOLOGICAL LABORATORY

September 16, 1954

Dr. Joshua Lederberg
Department of Genetics
College of Agriculture

The University of Wisconsin
Madison 6, Wisconsin

Dear Josh:

Sorry for the delay but I have been in transit, having arrived at
Cold Spring Harbor a little over a week ago. This is a “permanent change”.
In any case, I will probably be here for at least a year.

This automatically, of courses, prevents me from working with virulent
Pasteurella pestis. If time permits I intend to look for evidence for recombination
in P, pestis employing the growth factor requirements, rhamnose utilization, and
phage resistance as markers. I would be glad to communicate with Devignat when
I get into this phase of the work. I will be devoting most of my time (when
facilities become available) to a reexamination of mutations to itaconate and
mesaconate utilization in Pseudomonas fluorescens and the effect of such mutations
on the ability of the cells to oxidize TCA cycle compounds. This will be a
repeat of some of the work performed several years ago, which you ars familiar
with. This time, however, I will be working at the enzyme level and hope to
clear up the problem.

Do you happen to have Stanier's strain of Pseudomonas fluorescens A 3.7?
If so, I would appreciate a transplant.

Now that I am on the East Coast I hope 1 will be able to ses you when
you are in the neighborhood.

Sincerely yours,

“The:

Ellis Englesberg