THE ROCKEFELLER INSTITUTE FOR MEDICAL RESEARGH

667TH STREET AND YORK AVENUE
NEW YORK @I.N Y.

June 11, 1954

Dr. J, Lederberg
Department of Genetics
University of Wisconsin
Madison 6, Wisconsin

Dear Dr. Lederberg:

While looking through the Michigan State College Veterinarian,
volume 14, 1954, page 154, I ran across a paper on "A Practical Poultry
Vaccination Program." The following statements - unsupported by documentary
evidence might be of interest to you.

"Diseases for which effective vaccines have been developed include
Newcastle disease, infectious bronchitis and fowl pox, The so-called
cholera-typhoid vaccines are practically worthless and have the added
disadvantage of producing a positive pullorum agglutination test in those
few birds which respond to the typhoid component."

Sincerely yours,
4
Rene J. Dubos

RJD/maw
ec/ Dr. A. M. Pappenheimer