UNIVERSITY OF CALIFORNIA

‘EPARTMENT OF PHYSIOLOGY
SCHOOL OF MEDICINE
BERKELEY 4, CALIFORNIA July el, 1999

Dr. Joshua Lederberg
University of Wisconsin
Department of Genetics
Madison, Wisconsin

Dear Dr. Lederberg:

IT have written a theoretical paper on the origin of sexuality
and should like to refer to the fact that E. coli conjugates. TI have
been hearing about your observations for a year or so, but have not
found any published statement, nor does my friend Ed Adelberg know of
any. If we have missed something, I should much appreciate a citation.

Your permission to make a statement merely that E. coli has
been observed to conjugate will be much appreciated. If you have a
paper in press, I should be most grateful for the citation and for
permission to list it among my references.

T have very mich appreciated receiving your reprints during
the past two years or so. I am tardily reciprocating with my own
under separate cover.

Very sincerely yours,
Mewes C. Dsl LK)

Ellsworth C. Dougherty, PheD.e,MeD.
Lecturer in Physiology