UNIVERSITY OF CALIFORNIA DEPARTMENT OF BACTERIOLOGY October 23, 1950 BERKELEY 4, CALIFORNIA AIR MAIL Dr, Joshua Lederberg Department of Genetics University of Wisconsin Madison, Wisconsin Dear Josh, I would like to plan a simple recombination experiment for our class in advanced microbiology, Since I have forgotten the specific details of doing such an experiment and since both Roger and I have appeared to have lost the mimeographed directions that you had given us, I wonder if you could send me such directions by return air mail and a couple of good stable mitants which give a striking differentiation in a fermentation character of the recombined prototroph, I will leave it to you to choose lactose or maltose as the differential character, I am gradually becoming adjusted to living in America in the second year of the oath, The fortunate action of the faculty in damming the majority of the Regents has created sufficient feeling of solidarity to prevent some of the decomposition that was going on in the faculty. I am happy to say that Roger has decided to remain with us and this makes a preat deal of difference for my future plans, Rita and Roger join me in sending Esther and yourself our warmest re- gards, Sincerely yours, Michael Doudoroff _ MD:his