R. Bruce Wallace Jan 3 1982 DNA as mutagen How thoughtful of you to recall what I wrote 20 years ago! The deeper my regrets that my calendar is fully booked for the time of your meeting. If it should open up unexpectedly I will write back to you. You may recall how Dobzhansky characterized the pneumococcus transformation as a "desired transformation" even before Avery and co. characterized DNA there. This may seem a semantic nicety but Avery (and Harriett Ephrussi) were informed by it in such a way that they avoided doing or interpreting multi-marker recombination expts. in a single, straightforward way; and this was left to Rollin Hotchkiss some years later. Best wishes, Joshua Lederberg