February 21, 1955

Dr. 0. H. Gaebler
Henry Ford Hospital
Detroit 2, Mich.

Dear Dr. Gaebler:

Thank you for yours of the 16th. The present arrangement, as foutlined
in your letter, qiite satisfactory. You can regard ay comnmitiint as
"peasonably final".

I do have some suggestions about possible attendante; probably somes of
these will already have been advanced. Most would be especially pertinent
to the first day&s sessions, and particularly to the genetio afternoon.

Dr. Charles Yanofsky, Dept. Microbiology, “estern Reserve University,
Cleveland 6, Ohio, has done perhaps the most critical study of gene-enzyme
relationships in Neurospora, and oan offer almost the only cogent support
for the "one-to-one" theory.

As you know, "blochemical genetics" intially developed largely through
Garrod's work and review on hereditary defects in human metabolism, And more
recently, the studies on "mtant hemoglobins" in man stand aa virtually unique
examples of specific gens-protein relationships. I would suggest Dr. James
Neel from the Heredity Clinic at Ann Arbor. Indeed, if it were not too late,
and there were time, I would strongly urge that he be asked to summarize the
hemoglobin studies from the viewpoint of that afternoon session, in a more
formal contribution.

Dr. Lardy may already have named fr. Boris Rotman from the Enzyme Institute
here. Dr. 8. Zamenhof at Columbia University (P&8) has studies that parallel
Dr. Hotchkiss’ topic, as does Dr. T. Puck at the Department of Biophysics,
U/Colo. (Denver). Dr. H. Lichstein at U.Minn. (Bact.) has expressed an interest
that I hope can be honored.

I will be accompanied by ay hife (Dr. E. M. Lederberg).

If I can think of any other names that would compel attention, I will let
you know.I found that most of my possible suggestions had been already anti-
cipated, and eppeareday as uschdduled spelikers.