THE ROCKEFELLER UNIVERSITY

pro bono humanis generis
1230 YORK AVENUE - NEW YORK, NEW YORK 10021-6399

OFFICE OF THE PRESIDENT
February 22, 1988

Dr. J. F. Crow

Dept. Genetics
University of Wisconsin
Madison

Dear Jim:

Are you game for another thrilling episode of commentary and recollection? I was please
to have had the opportunity of the piece that came out Sept. 87; though in retrospect I tried to
cover too much, of a subject that is historically and scientifically intricate (and arcane in some
places.)

What I have in mind now should be much more suitable as anecdote: reflections on indirect
selection and replica plating: (and mechanisms of adaptation in bacteria)

 

tT

Lederberg J., Lederberg E.M. Replica plating and indirect selection of bacterial mutants J.
Bacteriol. 63: 399-406. (1952)

Cavalli-Sforza L.L., Lederberg J. Isolation of preadaptive mutants in bacteria by sib
selection. Genetics 41: 367-381. (1956)

(and going back to
Luria, S. E., Delbruck, M. 1943. Mutations of bacteria from virus sensitivity to virus
resistance. Genetics 28:491-511)

 

 

 

I have most of the story in hand; if you are interested, let me know what deadline I should
aim for.

It was great fun being your companion (again) in Ann. Rev. Genetics.

rs.sincerely,

   
 
 

   

‘ Joshua Lederberg

Mum ~ Bo Pores ret § he
Ly fre Cemfies , autawer ?

rte
P,. 6 hinds
2 Kw, TERE Dn net as pod

Arrwed oT AW, “pays p279