UNIVERSITY OF WISCONSIN Department of Geneties Madison 6, Wis.
U.S.

Jamary 22, 1951.

Dr. F. M, Burnet,
Walter & Elisa Hall Institute of Medical Research,
Reyal Melbourne Hospital,
Parkville N2
Australia.

Dear Dr. Burnet:

You may recall having granted a request to republish ene of your
papere on lysogenicity in a reprint volume being sponsored by ths
University of Wisconsin Press. The project is now in an advaneed state
of preparation, and I am eoneerned now with obtaining formal permissions
from the copyright holders, and in setting up copy. I am about to ask
a considerable favor of you in this sennection, which I hope you will
notbhesitate to disapprove if it promises to be meh of a burden on your
eonvenience. The only justification for these requests is that they may help
to expedite these long-distance connections.

The first problem is to obtain formal approval for re-publication from
the proper copyright holders. The available issues of the Australian Jl.
of Experimental Biology and Medical Sclenes do not convey to me whether a
copyright exists, or failing that, te whom application should be made for
reprint~approval. May I ask you to secure this information for me? If you
could, at the same time, recomnend a letter of ccnsent addressed to me, it
would be of additional help in saving tin.

Secondly,~ the aatter of sopy. Our only copy cf your article is ina
bound volume with which I do not dare tamper. A suitable photographic copy
(which aust be of rather good quality to be rephotographed for the offset
plates) would tax our faeilities, and be rather expensive, although it
could be arranged. Is there any possibility that a reprint or two has sur-
vived, which we could borrow for eopy? Failing this, can you suggest whether
it would be possible to phrehase the issue in which your article appeared
(Mareh 1936) ? If so, I will be ghAd to remit any reasonable charm.

We were, of course, greatly disappointed that you were, afterjall,
unable to visit our institution. I hope that a more propitious occasion
will develop before too long. Of course, we were greatly excited by your
report on recombination in influenza, and hope that you are clarifying the
details. With E. coli, Mrs. Lederberg is studying the transmission of a
lysogenic phage in various crosses, with a system somewhat like the =~
SF-C-~C'. We have also found a large nusber of new, distinct strains which
ean be crossed with each other, and which provide much new material in which
the genetic differences ere of natural occurrence, rather than induced
mutations. We are also making cptological comparisons of haploid and
diploid bacteria (E. coli K-12 derivatives), and I am glad to be able to
say that{ the nuclear patterns are, in general, easily distinguishable,
although no simple interpretation in terms such as chromesome number is
yet possible. A student has also made very consider&ble progress in
erossing S. typhimurium, and sero-geneticg studies on all these systems
are under way.

May I express, in advance, my appreciation for whatever help you
will be able to offer in sonnection with the reprinting of the Burnet&Lush
'36 paper,
Sincerely,