Dear Ernsts

You will certainly be cetting the reprints you requested;
I do not see:how I have overlocked putting your name on our regular
list.

I was pleased to have your tentative reaction to the Syntex
proposal, fully realizing your concurrent interest in other possibilities.
meanwhile, there have been some changes in the details of Syntex's
policy, mainly advantageous to the research prospects, though the; may
fommiowes involve setting up initially in Ics Angeles rather than here.

I am anxious myself to accelerate the shift to Palo Alto as soon as pos-
sible; by the time Dr, Zaffarroni can see you, thede matters should be
firmly settled, and if he can convey am definite offer you will be able

to know exactly what the setup will be, There is also some question now
whether there will be (to start) a named director, or whether the adminis-
tratfion will be broken into the eperating groups (probably 4, 2 in organic
chemistry, 1 DNA biochemistry, 1 immunology). But these are all matters
which are not necessarily of the first importance and, in any case, should
be the subject of further discussion, In any event, I will be deeply

and personally concerned with the development of the research program
which, obviously, would have many paralkels in my own interests.

As to your remarks on tolerance, I would like to discuss them
with Nossal before making a detailed replg, I have the impres&hon that
Cinader obtained diametrically opposite results, but I may be overlooking
some details, Your second experiment seems to contradict the first one,
unless there is some additional basis to ‘horror autotoxicus’ than early
expeeure to self antigens,

XXXEREXEKAK Dr. Saffarroni should then be cetting in tough with you
in good time,

   

urs sincerely,

  

4’ Taderber~: