SY NTEX &&

Dr. Joshua Lederberg
716 Alvarado
Stanford, California

February 15, 1961

Dear Doctor Lederberg:

It is with great pleasure that I anticipate our meeting in Mexico
early next month. I hope neither our dismal weather here nor
your own schedule will interfere.

At Carl's suggestion, there are enclosed reprints of journal
advertisements which have appeared over the past few months as
a pre-marketing exposure of Syntex to U.S. physicians. Such
promotional material will be sent to you routinely -- and, as we
approach the actual introduction of products, we will include
your name on our lists to receive copies of everything sent to
physicians.

Also enclosed is a copy of a lay letter sent some time ago to
about 315 selected wholesale druggists in 49 states. This deals
in pure commerce, to be sure, and represents a complete depar-
ture from past industry practice. Before this came a string of
short notes to prepare the ground. After it came an enthusiastic
response beyond our expectations. Materials such as this will
reach you, too, for our efforts to gain reasonable distribution in
53, 000 retail pharmacies require considerable thought and effort.

Separately, I am sending the first five in the series of scientific
bulletins constructed for the training of our medical representa-
tives. These will seem bulky, but this impression is somewhat
misleading, for such bulletins actually reach the men in the

field either one at a time or in even smaller portions. Again, as
new bulletins are prepared, they'll be routinely forwarded to you.

There are two reasons for sending promotional and internal
materials to you. We'd like for you to sense the kind of pharma-
ceutical company we want Syntex to be, and invite your reactions.

With best wishes,
Sincerely yours,

a a

Edmund R. Beckwith, Jr.
Enclosures

EDMUND R. BECKWITH, Jr, President

SYNTEX LABORATORIES, INC.
10 EAST 40th STREET + NEW YORK 16, N. Y.
TELEPHONE: ORegon 9-410