April 2, 195)

Dr, “alter Carter

Pineapple Res. Institute of Hawaii
P.O. Sax 3166

Honolulu 2,

HAWAII, TH.

Dear Dr. Carter:

Thank you for your letter of April 12 and for the reprints wnich have just been
received, I have been extremely interested in your work on the mealy bug wilt of
pineapple since I ran inte it in the course of preparing a review on hereditary sym-
biosis a couple of years ago, As I ordinarily have little contact with the phyto=
pathological literature I would be indebted to you for contiming to keep me apprised
of your work in this field, As you may note from the enclosed book review, and from
the review previously mentioned, I am heartily sympathetic with your conclusions on
the significance of symbiosis, My approach to this question is however from the
viewpoint of microbial geretics rather than cytogenetics. I hope that it will some»
time be practical to conduct with your material the kind of cross-infection experiments
witich seem to me most vital.

I was especially intrigued by your experiment on the maternal inheritanec of
symbionts on the one hand, and in Eito's work on the determination of sexual Sunction
on the other, Has anything further been dore on these tovics?

According to my records, I made a special point of sending you a reprint of
the review "Cell genetics and hereditary symbiosis" which appeared in Physiological
Reviews in 1952, In view of the title and rather formidable nomenclature, it is
possible that you may have overlooked the particular reference to work within your
own interest. On the other hand, perhaps this reprint never reached YOu, @ point
that I would be interested to determine, Lf the paper was iost in the mails, T will
be happy to dip into a very limited residual supply to furnish a replacement,

You mentioned your aequaintanceship with the Huskins, Their loss was of course
keenly felt by everyone at the University, both from a personal and a professional
standpoint,

Yours sincerel
§

Joshua Lederberg,
Associate Professor of Senetics
JLemg

Enel. 43 poatcad

P.S. Did I say leafhopper? My slip.