August 9, 1989

Academician Vadim Ivanov

Shemyakin Institute of Bioorganic Chemistry
Yuri Shiyan

USSR Academy of Sciences

Dear Yuri and Academician Ivanov:

We are looking forward to the next BW meeting in Moscow October

6-8.

Here are our agenda proposals, and we hope to receive

agenda ideas from you too:

I.

II.

IV.

Further Consideration of Inspection Regimes (both sides make
presentations):

--which facilities might be inspected?

--what would be the content of disclosures about their
activities?

--further discussion of categorization of list of agents of
human disease and discussion of the specific numbers for
thresholds for disclosure and prohibition which American
side presented at last meeting.

--consideration of overall regime under which inspections
might be conducted. Progress on chemical weapons treaty
control and verification as a precedent: similarities and
differences.

--multilateral issues: issues that arise when such measures
are extended to all parties beyond the US and USSR.

Non-Proliferation: Feasibility of Export Controls on:
a. fermentation equipment suitable for hazardous agents
b. seed stocks
(both sides make presentations)

Self-Inspection (both sides make presentations): Discuss
ways to enhance and institutionalize self-inspection such as
legislative oversight, safety review boards, public
disclosures about activities, etc.

V. Scientific Exchanges (both sides present ideas)

a. Possibility of joint research program on variola genome
at CDC -- NAS side will report

b. Exchanges to promote epidemiologic surveillance

c. Additional exchanges to promote confidence

As we recall, your side agreed at the last meeting to do
homework for this meeting on many of the issues listed above.
We are interested to hear your more detailed responses to the
presentations our side made at the London meeting.

Our group could be available to stay an extra day or more should
you like to extend an invitation to visit an appropriate
facility or institute.
-2-

Attending on our side will be Dr. Lederberg, Dr. Chanock and his
wife, Dr. Shelokov, Dr. Monath, John Steinbruner, Victor
Rabinowitch and Lynn Rusten. We would be interested to know who
will participate on your side.

We are also interested to know whether Dr. Ivanov received any
responses from Americans to work in his lab, and whether he
received the the paper updating Dr. Shelokov's remarks on
inspecting facilities?

We look forward to hearing from you soon.
Sincerely,
Dr. Joshua Lederberg

Lynn Rusten
NAS USA