May 18, 1956

REPORT ON RESEARCH PROJECTS
for the
FISCAL YEAR 1955-56

 

 

I. Neme LEDERBERG Joshua Dept. Bens tics Proj. No,__ 932233
Title of project Genegics of bacteria
M. L. Wright
. R. E. Wright
II. Personnel: etsa Lino

III. Statement of other financial support, if any, for this project:

Nationalinstitates of Health § 500
Rockefeller Foundation 6 000

IV. Brief statement of specific progress made during the year:

1. Phase variation in Salmonella has been found to depend an reversible change of
state of a gene (Hp).

2. Position effect groups of Gal loci are being correlated with specific enzymes
(galactokinase ani UDPGal-transferase, respectively) but there are some exceptions.
3. BE. coli K~l2 mtants showing different patterns of segregation have been isolated.
4. A method for producing protoplasts in E, coli has been discovered, which indicates
that the mechanism of action of penicillin is to inhibit wall synthesis.

V. Publications that have appeared in print from July 1, 1955 to June 30, 1956.

See attached List

VI. Manuscripts accepted for publication but not yet printed:

See attached list

The pink copy should be returned to the Graduate School Office on or before
fugust 1, 1956. The blue copy is for your file,