WATIONAL SCIENCE FOUNDATION ADVISORY COMMITTEE
BIOLOGICAL AND MEDICAL SCIENCES

PROPOSAL RATING SHEET

No. Title Investigator Institutbn
B-3095 Genes in the metabolism of Taylor Hinton UCLA

nucleic acid

The crowth of Drosophila on a chemically defined medium in pure culture
and the application of now familiar techniques of nutritional analysis revre~
sent a problem that must be pursued somewhere in the United States. Dr. Hinton
appears to be virtually the only person who has contimed investigations in
this direction on a long-term basis. It must be admitted that this work has
been proceeding slowly if steadily, but nevertheless there can be little ques-
tion but that this research should be contimed, Some rather exciting results
concerning the nonchromosomal determination of nutritional requirements have
already accumilated and we may anticipate that in due course an interesting
structure of research information will be developed from these techniques, It
can probably be anticipated that a somewhat aceelerated pace of results will
develop as the techniques become more standardized, The level of operation ap-
pears to be reasonable for a project of this housekeeping complexity end I would
judge this application to be meritorious or highly meritorious, Judging from
the applicant's finarcial statement on page 18, support from the NSF will be
essential for the continuation of his work.

Score \ Signature
From 5 (low) to 1 (high)