STANFORD UNIVERSITY MEDICAL CENTER
STANFORD. CALIFORNIA 2257

 

 

STANFORD UNIVERSITY SCHOOL OF MEDICINE

Department of Geveiicc

15; 4197-5052 February 24, 1976

Dr. Louis P. Greenberg

Project Officer

Diagnosis Branch

Division of Cancer Biology and Diagnosis
National Cancer Institute

National Institutes of Health

Bethesda, Maryland 20014

Dear Dr. Greenberg: RE: Contract NO1-CB-43902

As requested by your letter of February 6th, we submit herewita
our scientific progress report for the period July 1, 1975 to
January 31, 1976.

We are involved in a careful reexamination for ourselves of what
we believe to be the most cogent options for further investigation,
besides the obvious necessity of completing the analysis and inter-
pretation of the data represented. We hope, at the time of the site
visit, to make more detailed comments, but the most evident challenges are:

a) To improve methods for the meaningful elicitation of significant
information that may be buried in complex computer tracings;

b) To clarify the significance of the association of BAIB excretion
with cancer, notwithstanding its occurrence in many normal
individuals;

c) To continue the examination of polyamines or other indicator
compounds if current analyses continue to validate our interest
in then.

We believe we have performed the central screening task that we had
agreed to for the present renewal term of this contract. However, we
are in the final stages of data analysis on this series; but hope to
have some more information in time for the visit.

Sincerely yours,

Joshua Lederberg
(Dictated by Joshua Lederberg
in his abs

 

Administrative Services Manager

JL/rr

LT. J. PO KENNEDY. JR. LARORATORIEs FOR MOLECULAR MEDICINE, DEDICATED TO RESEARCH IN MINTIAL RETARD ATION’

MOLECULAR BEOLOGY HEREDITY NEUROBIOLOGY DEVELOPMENTAL TCE DILINE

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