YALE UNIVERSITY OSBORN BOTANICAL LABORATORY NEW HAVEN, CONNECTICUT BYPERIVY’NTS IN THE GENETICS OF BACTERIA 1946- 1947. Joshue Lederberg. AUX ANOCRAT Joshue T.ederberg Osborn sotaniceal Labs., Yale University hew Haven, Conn. Ov ft & oe Coy ©¢ oO " Z oA a meee. en STACIL = B/axyo, —3/r¥ Y fé °. Teed IS6— lalinnes OM, aeerece part ito ¥ tet ao vislic. Auer 7P23, 33° lot Readeng ? 12h. Dud Vt “GAD. C-N He Ver Can U aa Ls c -— ~~ lth Hide HH —- -| + 4% - — Te OEE HE HEE ~ LOHR RH + t+ i tt Kel te HE OT t th] th dH] t+ HH) - + He | te HE] +4 HE] + (3,4 rhode teohid keith . Aw . | N Fz. Ms 4. » Cinder, hong ee AY fan He ae Ted ah can, J q p24. 26k, 1 oO | Ye et _ rach. —— ++ He mth V-0 Mb tth lune — + lok HO +E O ~~ Rees 4: bee Sb Lan tM. 246. Iot- BEL Vv TWD - + TCO) ee Ye Tye) thee Wit + de O rr Lt Text 160 PT thon Is], GPreé. jth. | 24h 0 Yb — — = 3/ b f Akal hinere able; ; fp Ut dhe be hat i : / 6 2 7 f | lake lcs Andon ( E -X ) avd / / ~6 haw lo . ‘ te eg of HC (a) (b) heakeding -/% “otaets. viele Ji o) tga, 1° frawcefer Haro dest Ho, ~2¥e a6 etistol, hie nw Ls. pute "58" (biticess € ext) mm r% on ok Poi — to cole ! St halt We hols heer . aa dueefoce (teal) BRI. bots unc beth dap tig noel hae Org Tart “wartucl age I fa berks, fopyinr ith /e ‘7 AH - anracorr _ mu - ’ . ' / Teat Ln1zd4e@wesd 7 ~ Z ’ de tie : fy bctiat 1 o- | ry2 - oe 164 Wfesb Dee a. | % 130 p2Ejuee . 430 art eo \ a F 4 f / ° 3/ 4 ALU Be ay Mel IZM 30 1B. 2. +P 4° " [24 B0Brer . . ) / pi ce . iP 3d iV/foAl S/F LN» poe a J L | ve+8| 7e-4 | tee -7 l42 -1) 2-36 WG.|—- 1- | 2 3 aa g 4 O cob VY _ J - 6. C. J66 0 Leg ( 2 elep } ple) 7 + hare ter Cling . Cuabed-sast collated, per oa Ou re GN HE, neal de hag ca bale. 4 HV Oger VG nyse io Nuon by aathen del ciiadulos 6 fe, Neneh ete, ce JOA d1 free Soack/irs ant Hal esi C- = 58 (hes . O 1 U dt e Co FT Ormh eo T, pended oj peas AS, Il een, fio fake 1) AEE thy, her Mk ute Sturckeeti (Sige Id ae vhelrg, | ny 2+ borer, Breage tro hgh | earner mana ee mae Pa et Se ee ntact ent oF 1:30.) a Al. Ure Ib7Al + wedate potnt, S mn, De wy; Hop, AQ, Cohinete | (4) sradiation pel SST + pel ute YG, la. b, atrkly, f- . TWIO, [1:50 4 |: 2 500 L125 000 I: 6450 000 Uf 167 te! . BARK LL? ty “oo a ; eo . 7 o Pe ZL , , a preketion hireen af ca. SO bet et 2 atie/, ) L350. / V / JF3/- Hate beat (ea /o°) sete (0) Tonga O-F ( hertihé) Fe frbaly an voting demas HC + berteline (/0 fo, ./% «aap. ) 4 Af | |. [oom 809. pe Mrerhot (Hl. furs. Af webbed TH lpr + wicubet: PY. Al Achaunee dure Pr.-¥ oe Poe Vinee wre. van we 4h -3. [rey 0 abr ¢ 2,4, 6 70 apa L uf 37 Uze plte ¢ an ater Orfee . fg a UJebe thes ior gar/ f bad. % Wh 196-7 -~ fl o/ue. 16 Fa fe: a f. beatatdb, Methel ¢ font (rgd LIS 4. Resapides capella He bal nen eh %, Lo alporums reine oro bectinn, bh ererLinbls peep H. Ve adhagad eblnvads atten tr acegcarap linn Hotlnt ( 63.) Sup. (61. Muumor HE, Vite ond. (dup. 160). Then, Hafod to calthe alen Ze | se matths tokio vn 0 Vi To a Kheprpeacences, Hah Green wtrienal) war meorh truant & hartins, Apgpecennthy om apport te HE ove pes Vv Ce twen cee lke, pet dng the nied earth on het las |!) The Sesnadasaactl oy natin | the paamnsion 2 0c leas Uhenthle nme Oe BD. Ge), Aiclesnagen aio tar Aliana Man, phltlane costs JN g /\ JX ae to be rhelech, tet tt ae oe +e Ns hacredt mek le & wad my 1 eae Brotin -y Metron: . R. Mute Kereesurins Aa are ca. fk fh. poets (CB. for) acter To ; rf " vidiiatid ate vnecubale Ye . ITD ' loses fs ea Reh tf ao Paki on '/Oa., wa apm f Nee tind : CH Hrs traccg wee a. /O% 53 (betu ). p weet: bokty feted E-6 aca § ct pecs cng | foe cely * Soe YS Wp — vm ye 13 /4 24 2L df. aL Bd yf. 42. = 7 171 [7 2% My, - Utlpeabeotion' bee /bTA,. Prodkialie SF egli. Sian at tlm uiguedt, tech py bout Isrbiim before setabinte; nk. Leet BE (810°) cle ldsS)= 5.7 x04 /e (1¥9) 2 3022701 W447. + 23 %70% le (124) = Joye 0" iid 14. Boo = 375x104 Q52)+3,/ x0! * 3 oe PL 4, 3 2 3.65/04 2.6 3x 10% = | Ne ; foe 7K /0~ Merwe = Line. = 3 x/0 4 - —7 ~ 2 x/0 00002 to survival. aj Simm. (Bac Huse wre wre ot Softech afin Sra, Hesse eel be latero gtasacts i Wn UrV Aen Aahar 1S hereco + Leff jas x04 (ap) bot & u; Ta). WidoPG. , JLiPoAT. Py whats (ta. (*/.) du bee . LSe 83 | 3 pootun . S nwa u, lloo cello s |bow. ? pet | founh Ry Sf Ss" 7. uy. Ss. g yoo 172L TGA) | He | ts. | beeyanedy, K-12 O Oo +> Ly tk ; 3 @D 5, Ll “ 3 Oo . ZL ' ed is 3f ‘ [6 oO ge ' 3? 3 3Y 10 - 71 " oO oO 4 ' 43 3 44 10. _ 15 1: A war. [te 45. v ake D+ cata > ¥ > oo Lge 0 ka dk AW Zi hes Berrie 38° [bir boergumnty : xt 3 Dil 1: 50,52, 500 = teteptemeen, 2 aa) O b(n) wo 25% 7. T(646) (Wb penn te AG t t rei +l | ett. ll I: 2,329, 029, oF - 80 Lv. L273 ¢Z, Retin, .OlV. ot AOR EU febes). Tile Fo he 15, - / qa _ 43, — 57° H+ g — 83 tHe Tha +++ 75 +++ 14" — q3 +. 63 +e 67 t+ G4 +++ 42 + ‘13° +++ go" +15 que — q\' + 4> — do. _ 73° VERE x Lior @ TyA FPA. Ft KIL O Q for > 2 O oO (cor 53 10%r oO (00 ro L {vO Vr oO (sor 79 oO /O (oor 76 oO (qov iaqor 77 /6¢ for (CO 5§ 5F-278 tk © 2 7 or © ° 60 /0OY © © é/ /Or {coYr Oo 62 lor a /or iad 10V o Sor f Jor o Joo és °o *~ 760 ¢- 66 /GoK oO for 67 [tor ° 2,or 68 floor o (dor $7 /O}, sor 100 & Jo oO oO Sor 00 v7 S8- Wi oo o look 72 J€- 5030 o ro] (00 73 0 [0 o 77. /oo fo ° 4fi4. (ttitqe bins / EPA: Sf $P-277 /0 PL (ow 93 5Hh~¥H94 10 #Y ju? ES S#-5030 i) #6 10c7oO * fot on 30° 3 oe 7P%2U PLS q7 ~ 467 _ q7 - - -~>3 G5 TSF tt geen bic) - G7 gs! * ype purines : the pere. 1 fF 3 \n? \w pon Prev 58-218 Af. b 12,580,000 ale To) ter anin etal Ah 820 PIF. Cound, af p- Colony a Pusedr0 9% JOA 21 a gezty2erl Cop i i a “— ‘ > t4+ bcrdusble vauslin . — ! 4 <— do 362, 3 130 3 7 + 352 Fq3A2e mF < #1, woe 379 1d 3 = do. yor (412) g2°p 22 2% — t+ H+ 363 & “ 23 — — G10 ALI 36 — 24 té + .3h0. ey ro § P21 4%. ++ sya, " thee ietler, teloreis e orebtoaroee. pak G53, n+ Ing 6 6 ". [hover vs bale be brag hon plese h IC. Pat Lb acs ag GP 20: chrarces o: an etree. Poree hotles, Prorkean fom 4 pep litie: . Ireubete 20°. Z! Pro + ++ t+ +++ oO 13 = Le Yee. + 4+ + +++ oO 139 - 23 P21 + + tt 16 38 +! z¥ P21 + + yt le ist + Ls epg ~ + +++ 13 ISU. + ey 2% 8F2¢ ~ + + 23 1330 ~ 7. LT QRAr2D gore eps re o 139 = we j23 -§7 Gapr~s 7:15P-- Enis pot di Meee. selcsten(3-5 bi) a4 Is. +7h apf 3011304 24. 26. ee choice de ¢( WS +£ 31 ° ens -KL. 1s - 32 “ OY 38°) nS ie ae 340. (2+) By CHP. + +44 o 446 + 34 Dihitet + ae oO 143 + af.” + +4 Oo 128+ WAL. FAPLI \LM2l Joa~ar~zra pr3% A. Corel. = 2. 24 m= 140. 1@49T. 6 AE ES g° 4, Vaeltic 1 56- 278 aft d pa cyeelluh fer 4 18 bene. ey + Tawa chorucs uRX [oP rd pron chine « Riek trborris Nf 20. au \44. HS = (nun.