April 10, 1957

Dr. J. A. Jenkins
Department of Genetics
University of California
Berkeley 4, Calif.

Dear Jia:

The best review, such as it is, of streptomycin effects on chloroplasts
is in Provasoli et al., 1951 Gold Spring Harbor Symposius. Shée—alec-refers
Von Buler has a fragment dealing with effects on higher plants in
Hoppe-Zeylers Ztachr. physiol. chem. 295:411.

A Dr. Nancy Ziebur did a little work here with som planté, but did not
go far enough to get anything conclusive. Her best method of application

re to be agar caps containing .5 - 1Xmstreptomycin, applied to growing
points.

No one here is working on this now, ami as I think you gathered, I'm
rather enthusiastic about the import of the problem. The more so if there
could be som useful side-issues.

To revert to Euglena, you aight be particularly interested in the complex
relations between ths mamrka carotdnoid eyespot and the chlowoplast. These
are toughed dpon in the Provasoli paper, in som contributions by Pringshein
(New Phytologist 1952), and to illustrate what I'm talking about, in my
review in Phyaiol. Revhews, 1952.

I did appreciate the hosphtality you ani K. showed m.
, Beat wishes

. —
ehua Lederberg

Ad