ACME Computing Facility
| “Advanced Computer for Medical Research

Stanford University pans of Medicine

ANNUAL REPORT
“FY, 1972

Primary support from
Biotechnology Resources Branch ~

National Institutes of Health
NATIONAL INSTITUTES OF HEALTH
DIVISION OF RESEARCH RESOURCES

BIOTECHNOLOGY RESOURCES BRANCH

RESOURCE IDENTIFICATION

 

 

 

 

 

 

 

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Report Period: Grant No,
As +e .
From: August 1, 1971 To: July 31, 1972 RR - 311 - 06
“s Date of Report Preparation:
May 1972
Name of Resource Resource Address Resource Telephone No.
Advanced Computer for MEdical | Stanford University (415) 321-1200 ext. 6121
Research (ACME) School of Medicine
Stanford, Calif. 94305
Principal Investigator Title Academic Dept.
Lederberg, Joshua Professor Genetics
Grantee Institution Type of Institution Investigator's
: Telephone No,
Stanford University Private Non-Profit University
School of Medicine (415) 321-1200 ext. 5801

 

 

 

Name of Institution's Biotechnology Resource Advisory Committee:
ACME Policy Committee

Membership of Biotechnology Resource Advisory Committee:

Name Title Department Institution
*Elliott Levinthal Assoc. Dean for Research Genetics SU Med School
Stanley Cohen Assistant Professor Clin. Pharmacology "

Joseph DeGrazia Assistant Professor Nuclear Medicine "

Donald Harrison Associate Professor Cardiology "

Sumner Kalman Professor Pharmacology "

Howard Sussman Assistant Professor Pathology "

*Chariman; has reviewed report.

 

Name and Title of Principal Investigator

 

 

tepesare Date

Name and Title of Grantee Institution Official} Signature ) Date

Joshua Lederberg, Prof. of Genetics

  

 

 

 

 

 
TABLE OF CONTENTS

TMTRODUCTION. a cacscccccccncccccwweccccs ccascassccncesccncccccceel

i.

Ii.

Itt.

IV.

SUMMARY... cece ccc ccc cc cc ncccccccnscccncucececcecccuccacccncd

A. Highlights of Piscal Year, 1972... cccscccccencccecsecesld
Be Goals for Piscal Year, 1973... cccccccccccacccccecescces3
C. Comment on Medical Center Coaputer Planning. ........0.04
D. Overview of Six-Year ACHE Experiment... ....cccccccesccecd
STANFORD MEDICAL CEWTER COMPUTING PLANS. gc cccccccccccccccee?
A. The Sedical Center Scene... .ccccoccccccccccaccacesccecel
Bo ACME FoOllOW-On Grant.ceccccccceccccccrcccscccsccvesesscel
ACME FACILITY ACCOMPLISHMBETS, 197 2eccccccncccencccacccsceed
A. Planning StudieS.....ccccccccccccccccececcccccccccececed
B. ew and Continuing Application Programs......ccceececee ll
C. System Software Improvements... ..cccoenccccasccccesccee t3
D. Hardware Changes... cccsacccccccccccccccacccsccccccccce lt?
E. Operations Report. ccccccccccee cccscccsnccsecscccccccesell
Po. Education and Training. .ccccecceccscccccccccccsccascavela
PLANNED PROGRAM POR 1973.2 cccccccccccccccecccccccccccccess 24
An ODJECCIVES cc reer ecccccccccccccccancccccccccccecacacsces 24
B. Applications Development... ....ccccccccccccccccccccese ltt
Cc. Hardware ACQUISITIONS. oo cere ecewe scene sccceseccceeceee 2
De. System Software... ccc cc ccaccccccccccccccccccccccccse eld

ADMINISTRATIVE ORGANIZATION. ccc cca cccccccecccccncseccesseed3
(ii)

VI. BUDGET 2. ce cc cc cw mec ccc mecca c wc c ccc cece wesc ccececscccesccse JD
Aw. Resource Expenditures. .cwaccccccacccscccrccccseaccccs 39
B. Justification for 1973 Budget. .... cca ccccccccccccecee 36
C. Expenditure Details. ...cseesesccccccsescscaccrccssccee 38
D. Summary of Resource Funding... ccccsccsccccavcccccssees 43
E. Resource Equipment LiStecsccccccccccceccccccccaccccees 44
Fo Income Projection. 2. ccccccscccncccccccccccccscccccccce 4/7
VIL. PROJECT DESCRIPTIONS... cc ccccccc ccs ccccccscccccccccsccccccs 49
A. Core and Collaborative Research... .cccccccccccacsc cece s 49
Bo SeLVice Projects... 2. cece ccc ccc ccccancccccecccccccscsee 56
Cw. Training Project. ence ccccccccccccccccccccccccscessces 18
VIII. UTILIZATION DATA. cc cc cc ccc ccc cccncccc ence cesses asececcess G2
A. Interpreting Utilization Charts... cece cccccaccncccccee 82
B. PatternS Of USC... cc cccccccccc acca nanccsacecsecccccces B3
Cw. Utilization Charts... wc ccccccccccnccnscccccccccccccsce 85
D. Summary of Computer Resource USage...cccccccsccccccece 89
IX. PUBLICATIONS... cc cc cc cc cc cc cc ccc ccswccncascncsaccccesccesecelll
A. Publications in Regularly Scheduled Periodicals.......111
Be Other Publications. .cccsccacccncaccccccacvcccscceceesall2
Cw. Staff Technical Notes... .cccccccaccccccccccccscascces cll]
Appendix A: Summary of Campus/ACME Merger Study......... 223
Appendix B: ACME System Core Timing Results...eccneecece 0l28
Appendix C: Results of Three Compaction Algorithas...... .136
Appendix D: Comparison of Meantime Between Pailures......137

Appendix E: Proposal for Ssall Computer Service......... .138
(iii)

Major portions of this report were prepared
using the Stanford Campus Facility WYLBOR
and ACME Facility text editing prograas.
Final copy was produced on the ACMB systen
printer.