Lt ae A be GAL

Hence on present and future potential scaie ol utilization ci analo: -toedi; ital
& comanit. =

tacilities in the medical schuol.

 

Gver @ Lerio!l of a iew weeks, Prolessor Linculn BH. Moses oi the Statistics

4

Departucnt interviewec several research worhers at the medical school. ‘fy .ically,

these discussions lasted lor about an hour. He vound many investipators exoress=

ae

in: a direct interest in the imrmediste or near future availability of analc, -to-

‘

ad:ital equigaent for marin. availaole the services ci the Cum utaticn Center.

These discussions will ve summarized oy suoject area.

Keart

 

David. Rytand, Proiessor of Medicine, has lon veen interested in atrial
Jioriliation. This disease is characterized by an irre;ular E.C.G. and oy a lac.
o. coordination vetween the upper and lower heart. By wieans cl takin; readin s on
highes eed recordin, a,paratus durin, cpen heart sur,ery, Dr. Rytand has ovstained

recoris which shculd oe valuable in testing medeis for the mechania: «1 strial

 

auwpiilaticn. A central preplem in all this is the question cf
this analcs record. He would make immediate and probauvly extensive use cz such
lacliities as soon as they vecame availaszle.

J. von der Groven an’ Dr. J. G. Toole have ior same years seen encaced in
aneiysing £.C.G. records by means of choosin: orthogonal axes and rebtting a
readily interpreted vector representative of the heart beat. In this wor, sane ci
Which is in clinical use (dia nosis of certain lesions) they have nocessarily Jone
@ ¢reat auount of analo, -toedicgital data reduction, mich of it wy hani. They
anticipate that their research work in this area will continue, eroracing more
end more carticular dlagnustic provlens. The exolorater, alysis, testing or
trial hypctheses and so fourth would ve greatly lacilitated vy the
food equiyaent of the type contemplated. They would make inmedzate an extensive
use cl such equinnent.

/Contd.....
h

Molecular Biclo:y

In the Bloyhysics Laboratory, Professor Howard Pattee is enga-sed upon
developing an Xeray adifvraction technique and hardware for studyin: the structure
Go. tacranclecules. It is more than provable that in the acar Luturc, he will
have orought this work tc such a point that two iinds oF proolamn relevant to the
project proposal will came out of His lab. ‘The first of these is a need vor
digital-tc-analo; equipment tor inverring contour mars of a sort Prem an analytival
moiel, The second is a need for analo-toedigital equinent for processing the

analo., data which arise cut of scanning: the X*ray micrographs presaratory te

nunerical analysis.

Genetics
Proiesscr Lederberg has lnportant research hypotheses, the testin, oi which
depends upon verifying the occurrence or nonecceurrence of events havin,.
“)

provavilitics such as 190 ~. The data consist cf cultures or microscope slides

¢ other such systems which must ve read vy human ooservers. On so iarie a +

 

this is cut ci practical reach. Automaticn of such roading process vy eleetroni.
devices on tc tiagnetic tape, for exampic, leads to laze scale utilisation of
exactly the sort cf facilities under consideration. In the 1 run, of course,
as such autazacion problems are solvec, they woul’. ve handled oy s cclaily
develoved, less versatile, more eliicient and less expensive special cur oss
equirmens, out the develommental stages require large capacity, general yur lose

equipmcnt.

5 os

Proiesscr Lederserg's associate, Dr. levinthal, is the center of an
electronic en ineeriny group in the medical school and it is his view that the
presence ci this grouy will increase the number and variety ani use of analu -

data-croducin, equimment and research programe in the medical schocl., This
aw og

/Contdesses
precisvoses him tc recard as desirable y Ob least in the foresecavle Diture y vole
2tovision of large capacity, high quality A-D oquimment. He also icelis that

as the Lecorver, ~Levinthal oxooiclo.y uror rem de

 

of

nocessariiy .cncrate data callin: for the use of such equipment.

Keurolo-ical Rescarch

 

De. Karl Pribram is doing rescarch on learning, and gonerates soth digital
and analo: data. His emphasis at the oresent time is on exper huents Lleadin; to

dijita. date and this is partiy vecause oi the lack of analogetoell; ital equip-

   

ment. Ve stated that is the Cauputer Center now hati the equiznent unjer considera.
ticn, he wou. imiediately avply tor the recordin; equizment necded at the
lascratory am within three months woul. se using it heavily with =.5.G. and
ether sinllar hinds oi data.

De. fran. horreii's research vrojrari is iarcely -ased on the S.E.G. and he
Was very cutspor/en in his vellel that this cquizment is desiravle to his research
jécGives an) that he would mace use ol it. He weleame the choice of equbome ns
items Which uay eventually allow the use of real time.

De. Keith Killen, a peychc-pharmacclogist, is associated with Se. Priore.

anu De. Morrell in an application to the N.I.E. for a small scale analc--tc-
dijital gacility, camplete with dipital cousuter and digital-to-analsc. conversion
unit, etc. he feels that such a smali scale installation has advantages of
Bimeiicity, (uaking entry of non-nathuuatical viciojists inte this sind o wor:
easicr), tlexioility, (bein: easier tc use in exploratory worl. at the Laporatory )
a convenience (2¢in, under the control of the research erou, using it). At the
Sale tine, he made it civar that he considers the application in question te ve
Cum, Lenicntary to, rather than caipetitive with, the equlasent ior which his aPouL

7

dic anticipates contidently that he will make considerapic use of

 

che large capacity facilities which are the suoject of this request, ag the usc
of the small scale equiyment he has alrcady undertalen toe cbtain leas to clear’ oy

tormmilate? hy, ctheses and schenies of analysis.