OFFICE MEMORANDUM @ STANFORD UNIVERSITY © OFFICE MEMORANDUM e@ STANFORD UNIVERSITY e@ OFFICE MEMORANDUM
mec 2 1973

DATE: November 30, 1973

To . Joshua Lederberg, Department of Genetics
Carl Djerassi, Department of Chemistry

ROM Eugene D. Robin, M.D., Department of Respriatory Medicine

Sugject, YOur memo of November 20, 1973 describing a proposed GC/HRMS facility.

I have applied to the NIH for a continuation of my research grant, Adaptations
To 09 2 Depl etion in which I have proposed to measure the redox state of NADt/NADH
and NADPT/NADPH by measuring the ratio of oxidized to reduced redox pairs using g
gas chromatography/mass spectrometry. These analyses will be conducted with

the assistance of Drs. Alan Duffield and Wilfred Pereira of the Department of
Genetics. I welcome the opportunity to have a GC/HRMS facility available on
campus to support the GC/LRMS available in the department of genetics. The
facility you propose to establish will be of importance to us in those

instances where assignment of molecular composition to ionized fragments is
crucial for mass spectral interpretation. I would anticipate using this service
between one and two times a month.

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Sincerely yours,

veal D. Robin, M.D.

Professor of Medicine and Physiology

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