1/27/54
Dear Josh:
Could I promote a constitutive[?] Luc. strain?  We are pretty certain that K-12 differs from Monod's in that the basal level in K-12 appears to be a minimal unit of lucclare/cell rather than simply the presence of constitutives - and furthermore adaptation appears homogeneous in K-12 rather than heterogeneous as Bezer found.  However we need a constitutive Luc M and have been unable to pick one up.  Thus if
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you could send a transfer of yours we would appreciate it.
You might be interested to know that y-52 turns out to not be a Luc mutant.  The best dope we can get on it suggests  its a permeability affecting glucose as well as lactose. We do, however, have a complete Lac strain - no enzymes under any circumstance.
I understand you are now a home and estate owner - congratulations.
Best regards
as ever
Dave