Reply to Attn of National Aeronautics and - Space Administration EFLLLR uy VES NASA Ames Research Center wy Moffett Field, California 94035 JUN 27' 1383 Op, sf SE OF THE SCE OF THE pRESEA SS . LX: 239-11 June 21, 1983 Dr. Joshua Lederberg President The Rockefeller University 1238 York Avenue New York, NY 169821 Dear Dr. Lederberg: Twenty five years have passed since you and D.B. Cowie first suggested in an article in Science (Volume 127, p. 1473, 1958) that cosmic dust containing organic matter formed in stars and interstellar clouds might be found on the Moon. As it turned out, most of the hydrogen, carbon, nitrogen and methane on the Moon's surface does appear to have originated in a star; their presence in lunar soils is the result of ion implantation by the solar wind. During these years complex organic compounds have been discovered in interstellar clouds, and understanding of both star formation within these clouds and of ejection of matter from stars into them has grown out of new astronomical observations and theory. Moreover, the study of meteorites has revealed isotopic anomalies in the noble gases, in the rock-forming elements of mineral phases, and in the biogenic elements (H, C, N) of organic matter. These anomalies have not been understood in terms of known processes in the solar system. They are attributable, however, to origins in stars and interstellar clouds. Just as you and D.B. Cowie anticipated 25 years ago, there is a discernable chain of events involving the major elements essential to life that extends backward in time beyond the Planetary epoch to their very birth in stars. Elucidation of the links in this chain is the subject of the enclosed draft report prepared by the Study Group on the Cosmic History of the Biogenic Elements and Compounds. The Study Group brought together for the first time scientists from diverse disciplines to consider the physical and chemical pathways taken by the biogenic elements and their compounds from origins in stars to incorporation in the building blocks of planets. This report addresses many of the pertinent scientific issues, and it identifies the opportunities that exist for fruitful research across many disciplines. As noted in the Introduction to the report, it "is intended to serve as a scientific guide both for investigators interested in conducting research in the cosmic history context and for the Life Sciences Division of NASA Headqaurters in its development of this new program component" for Exobiology. On behalf of the Study Group and its Chairman, John Wood, I am a pleased to invite you to write a preface for this report. From the historical perspective of your involvement in NASA's Exobiology program, and your early insight into this cosmic history, you seemed to be the most appropriate person to make this contribution. Your remarks from the viewpoint of a biologist would provide valuable counterpoint for a report that has been prepared by physicists, chemists and geologists. Should you decide to accept this invitation, we would like to wa have your contribution at Ames Research Center by the end of August in order to meet publication schedules. I will be traveling on business until July 27. During my absence, please contact John Wood at the Harvard-Smithsonian Astrophysical Observatory, 6@ Garden Street, Cambridge, MA 62138, phone number (617/495-7278) if you have any questions about the report or your anticipated preface for it. With best regards. Sincerely, Sherwood Chang Assistant Chief for Science and Technology Extraterrestrial Research Division Enclosure: As described cc: J. Wood