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ENVIRONMENTAL PROTECTION AGENCY 2 2 2f5
Rockville, Maryland 20852

JAN S 7 S79

Radiation Office

Dr. Joshua Lederberg
Department of Genetics
School of Medicine

Stanford University
Stanford, California 94305

Dear Dr. Lederberg:

As you may be aware an advisory committee of the National
Research Council-National Academy of Sciences is carrying
out a comprehensive review of the effects of ionizing
radiation upon human populations. The NRC/NAS has invited
the scientific community to submit current data on the
somatic, genetic and environmental effects of low-level
ionizing radiation, including effects on human growth and
development. It has been requested that material be
provided whether or not it has been published, but work
in progress that has yet to be reported is, of course, of
particular interest to the NRC/NAS committee.

Recently Marv Legator, recognizing my interest in this area,
sent to me a copy of a report that you have prepared entitled
"Cost Analysis of Genetic Diseases from Radiation; $100

per man-rad," dated December 3, 1970.

In reading this it occurred to me that this report would be
of particular interest to the NRC/NAS committee in its
deliberations on the genetic effects of low-level ionizing
radiation. Therefore, I would like to suggest that a copy of
this report be made available to this advisory committee. If
you agree, may I suggest that you send a copy of this report
and any other information or data that you think appropriate
to the Division of Medical Sciences, Attention: Dr. A.W. Hilberg,
National Academy of Sciences, 2101 Constitution Avenue,
Washington, D.C. 20418. I suggest that a copy also be sent
to Dr. James F. Crow, chairman of the NRC/NAS subcommittee

on genetic effects. Alternatively, with your concurrence,

I would be pleased to forward a copy of your report to the
NRC/NAS committee.

With kind regards,

Sincerely yours,

pisien Hons?
arthur H. Wolff7*
Acting Deputy Commissioner
cc: Dr. Legator