mua Lederbes
ical School

@ University
to, Calif,

  

   

 

 

to express Ly Aapprecia
pesticides and their b

sus. JT an in complete a

ditional research on the
ag an entorolosist-seneticist=toxic
earga--and as one who needs a plece
ature of vicrosoral induction,
on oF genetle approaches with house flies, I have prepared
pe @ proving very useful in this research. ‘Thus, I heve
"33 3 (tnose vith umisua Ally hich oxidative activity), nODpU-
do sily inducible, and eleo populations which are resistant
to ides. Work soon to be published nave shown a surprising
ab: esistant populations, They nossess about two tines the
ue se-S-phoephate dohydroceasae activity and utilige the
pen an unusually high degree in metabolizing infected slucoce,
The is quite clear--resistance to inducers and high G-6-PD
lev le.
It = ty hope trat further work with these populations tight shed much Licht
on the mechanisrs controlling detoxifying enzywes in aninals and possibly, on
the | nature of reszonses to stress, Further, I sussest that house fly posu-
lations with their easy uaintenance and hish level of sensti 1203
enould prove ideal for this vork,

 

Bax you Lor your consideration,

 

1953 ,

Pony rap nt 3 “

 

a . f
WO bbe CLA aa. ~e Lad. ra