OAK RIDGE NATIONAL LABORATORY OPERATED BY UNION CARBIDE NUCLEAR COMPANY Tre) CARBIDE POST OFFICE BOX Y OAK RIDGE, TENNESSEE July 3, 1968 Dr. Joshua Lederberg Department of Medical Genetics Stanford University School of Medicine Stanford, California 94305 Dear Dr. Lederberg: In your newspaper column you recently discussed the work of Dr. James Cleaver on repair replication in Xeroderma pigmentosum. I therefore thought you might perhaps be interested in the results of our studies on the excision of ultraviolet-induced pyrimidine dimers in human cells. We have wished for sometime to extend these studies to the cells of Xeroderma but as yet have been unable to secure suitable cell cultures for this purpose. I read your columns with interest and hope you will continue them. Yours truly, ames*’D. Regan lology Division JDR:fy Ene losure