re -/ May 18, 1965 Dr. John R. Beem Associate Director for Progran Planning & Selentific Information National Heart Institute National Institutes of Health Bethesda, Maryland 20014 Dear Dr. Been: Thank you for sending me the hearings I asked for. The timidity of the approach to the kidney is too obvious, though there is some merit to the idea that more fundamental information is nedded for optimum design. But the same argument might have suppressed winged aircraft whikeerockets were being developed. However, I am sure the heart program will set the pace in bringing about the most important revisions of policy on development projects. Sincerely yours, Joshua Lederberg Professor of Genetics