FeB 10 ig64 EXECUTIVE OFFICE OF THE PRESIDENT OFFICE OF SCIENCE AND TECHNOLOGY WASHINGTON January 24, 1964 Dear Josh: As my period of service as Special Assistant to the President and Director of the Office of Science and Technology draws to a close, I would like to thank you for your willingness to participate in the work of this office and of the President's Science Advisory Committee. There have been many expressions of appreciation from President Kennedy, President Johnson and senior officials of the government for the contributions of this office to understanding and resolution of major issues of national policy and programs. These accomplish- ments would not have been possible without the direct participation = of consultants who have given so generously of their time and have a responded unhesitatingly to requests for assistance. I leave with ~~ the firm conviction that the continuing vigor and balance of scientific i S and technical advice at the Presidential level depends on the ability fy of this office to maintain strong ties with the most creative and capable * members of the scientific and engineering community. o My successor, Dr. Donald Hornig, will need to review with the Presi- 7 dent's Science Advisory Committee the activities of this office, the a existing panel structure and arrangements for consultants, bearing in mind the changing problems of the office. In closing, may I express to you again my very great appreciation for your help. Sincerely y Jerome B. iesner Dr. Joshua Lederberg Department of Genetics School of Medicine Stanford University Palo Alto, California 94305