MEMORIAL SLOAN-KETTERING CANCER CENTER 1275 YORK AVENUE, NEW YORK, NEW YORK 10021 CANCER January 23, 1979 Joshua Lederberg, M.D. Rockefeller University 525 East 68th Street New York, New York 10021 Dear Josh: It was a pleasure to review our research interests with you and to explore possible areas of overlap of interest and potential endeavor. I will keep you informed over the progress of the psycho- endocrine study with Jack Fishman of men with testicular cancer and their wives. While we have only clinical projects in the area of depression currently, this has a high priority in my plans for biologic research activities and, indeed, we are currently collaborating with Dr. Martin Sonenberg, Chief of Endocrinology at Memorial, who has a new technique for assess- ing catecholamine receptors in platelets that has not been studied as yet in primary affective disorders. I am very pleased to hear about the two programs that you are exploring to develp an area of research ip biological psych- = jiatry and to develop a Clinical Research Scholar program. I . ff would be very happy to serve on the Search Committee representing / psychiatry at Memorial, if one is formed to search for a senior S person in psychiatry. With your approval, I would like to approach some friends for the names of individuals whom they would consider particularly good in research in depression affective disorder. The Clinical Research Scholar program sounds exciting and I will pursue possible candidates with Gregory Gorzynski and Jack Fishman, to identify someone who might qualify for what should be an exciting and potentially important program for training young faculty in research which crosses fields and requires the gaining of expertise in several different areas. Sincerely, y Jigmie Holland, M.D. eee Chief, Psychiatry Service JH: la MEMORIAL HOSPITAL FOR CANCER AND ALLIED DISEASES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH SLOAN-KETTERING DIVISION, GRADUATE SCHOOL OF MEDICAL SCIENCES, CORNELL UNIVERSITY