March 5, 1975 Dr. Paul Lovett University of Maryland Baltimore Co. Campus Department of Biological Sciences Catonsville, Maryland 21228 Dear Dr. Lovett, It looks as if our experiments on the coupling of B. subtilis segments to pscl0Ol are bureaucratically too hazardous to be pursued in the atmosphere of the Asilomar final report. One way we might restart would be to use one of your newly discovered Bacillus plasmids instead. And Frank Young is working hard to produce a “disarmed" strain of B. subtilis. Could I ask you to furnish what might be useful by way of strains and information concerning your recent discoveries, You may be sure we will await the publication of your own report on these agents before making public reference to them ourselves, Sincerely yours, Joshua Lederber? Professor of Genetics JL/rr aed | liane