Department of Nutrition QUEEN BLIZABETH COLLEGE, Campden Hill Road, London, W.8. 5th February, 1958, Dear. Joshua, I am extremely anxious to know whether you have been able to get transformation in the coli I sent you Some time ago. I would appreciate very much if you would, in confidence, simply let me know whether you have done some tests and whether the answer is yes or no, With kind regards, Yours sine erely, pe Professor J. Lederberg, Department of Medical Genetics, University of Wisconsin, Madison 6, Wis., U.S.A.