FEB 1 STANFORD UNIVERSITY £B11 1965 MEDICAL CENTER PALO ALTO, CALIFORNIA SCHOOL OF MEDICINE DEPARTMENT OF GENETICS Professor J, Lederberg, Executive February 8, 1965 Professor Donald Kennedy Dept. of Biological Sciences Stanford University Dear Don: Concerning CHARLES YANOFSKY and his qualifica- tions as an outstanding scientist: his talents and accomplishments are so well known to both of us and to our mutual colleagues that it is very much a formality for me to be describing them to you. His work on the linear order of mutational changes in an enzyme protein corresponding to linear order of Sites in a gene is one of the most Significant contributions in recent years to both genetics and biochemistry. Besides the classic elegance of the underlying concept, its execution in the laboratory was a success of experimental finesse and hard work which has few parallels in scientific history. Although he is very well known and recognized among his seientific colleagues, he has been too modest to seek or encourage public acclaim, but I have no doubt that the beauty of his ‘work will come to be very widely recognized as an outstanding example of the best fruits of the convergence of genetics and chemistry. yf A N5 f0ely & Sincerely Tne ene ene