January 3, 1955

Professor H. Uetake
Sapporo, Japan

Dear Professor Uetake:

I have waited until now to reply to your letter of November 17
to learn from Dr. Porter about the acceptance of your manuscript.
It has now been formally approved for publication, but it will
take several months, of course, to appear in print. As I agreed
previously, I will correct the proofs when they are ready. I will
also forward to you the charges for reprints. I imagéne they will
cost between $0.05 and 0.10 each plus shipping charges. Unfortunately,
I do not have on hand any application forms for membership in the Society,
but will get one as soon as I can.

Iwas interested to hear from you on the subject of transduction with
E group phages. Not long ago, I had seen another paper by Isekdi and
Sakai on a similar topic. Of course fou are free to submit your manuscript
to Dr. Porter as the mitmt editor of the Journal of Bacteriology. I took
the liberty of intervening personally with regard to the last manuscript
bemause I thought it important to introduce American colleagues to your
work, but for future purposes, it would be best if you communicated with
the Editor in the mix usual channels. I will be happy, of course, t:
advise you in any way I can, as a fellow scientist. In view of the present
paper, and of Iseki's concurrent work, I am not sure that you should pub-
lish again so soon in the J. Bact. That is to say, the international ex-
change of mss., and the work of editing such contributions are sufficiently
difficult that I would candidly recommedd that you save the opportunity of
publishing here for the culmination of an extended program, and not for
current contributions at short intervals. However, you will have to reach
your own conclusion as to whether to submit any ms. to Dr. Porter, and I
can only assure you it will be considered fairly and objectively in com
parison with other mss. seeking publication.

You will recall Ghat I still had some questions on the mechanism of
lysogenic conversion in contrast to transduction: these still depend on
critical proof that each phage particle (say 100/100 tested), whether
grown on F, or Ep hosts, carries the potentiality of antigenic conversion.

This could be mosh seadily done py plating E, phage on EB, indicator, replating

single; plaqgeewead testing lysogenized bacteria corremponding to each of
100 plaques of the first plating.

With best wishes for the New Years