April 28, 195) Dr. Ek. V. Thimann Biological Laboratories Harvard University Cambridge 33 Massachusetts Dear Dr. Thimann: You may recall our correspondence last fall on a literature citation for the diagram of transduction that I had presented earlier at the local bacteriologists meeting. I do not know how far along you are with your mamuscript, and quite possibly this Letter comes too late to be of any use, I have however recently stuck my neck out on this interpretation, ard can suggest a spece ifie reference: my paper "Recombination in Bacteria" given April 1° at the Biology Research Conference on Senctic Recombination at Oak Ridge, Tennessee. Thig should appear in print us a supplement to the Journal of Cellular and Comparative Physiology during the next 4 to 12 months, This matter is of no creat importance, but I wantea the excuse t ask you whether you gad possibly thought of including a consideration of chemotaxis in your treatment of bacterial physiology. This 1s a subject that is not very welle known by most bacteriologists, most of the literature having ape peared around the turn of the century, With modern methods, I believe much more could be made of the problem, I will also take the occasion to acknowledge with thanks the private copies of the thesis and the reprint on small colony variants in yeast, I will of course return them to you ultinctely, Yours sincerely, Joshua Lederberg JL mg