UNIVERSITY of PENNSYLVANIA

DEPARTMENT OF HUMAN GENETICS

The School of Medicine/G3
37th and Hamilton Walk
Philadelphia, PA 19104

215-898-
December 20, 1985

Dr. Joshua Lederberg
The Rockfellow University
New York, NY 10021

Dear Josh:

Many thanks for letting me see the draft of your memoir on
Ed Tatum.

I think your discussion of Garrod's work is fair and correct. In
particular I agree with your statement on page 10 of the manuscript
that Garrod never quite voiced the intellectual leap from the anomaly
provoked by the mutant gene to the positive function of its normal
allele. Certainly when I was writing about Garrod in the early 1960's
I would certainly have quoted any explicit statement on this if I had
been able to find one.

I found your whole manuscript both fascinating and instructive.

£

Best regards.
Yours sincerely,
Harry Harris, M.D.
Harnwell Professor of
Human Genetics
HH/jb

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