ANNUAL REVIEW OF GENETICS

EDITORIAL COMMITTEE ANNUAL REVIEWS INC. EDITOR

CAMPBELL 4139 EL CAMINO WAY H. L, ROMAN
A. D. KAISER

A.

rary >

zZiro

. G. KNUDSON, JR.
MINTZ

« ROMAN
« RUDDLE
. SANDLER

PALO ALTO, CALIFORNIA 94306, USA ASSOCIATE EDITORS

A. CAMPBELL
(415) 493-4400 L. M. SANDLER

PRODUCTION EDITOR
T. HASKELL

December 20, 1977

Dr. Joshua Lederberg
Department of Genetics

Stanford University Medical School
Stanford, California 94305

Dear Josh:

I enjoyed reading your Tatum memoir for the American Philosophical
Society Yearbook. Bill Kaufmann is trying to get permission to have it

reprinted in the Annual Review of Genetics. I will keep you posted on
what happens.

AS ever,
Herschel L. Roman

HLR/nr
ce: Toni Haskell

Thank you, Hersch. DEC 271977

I did have one afterthought. Instead of (or in addition to?) the abovementioned,
I waka would like to write 4 or 5 pages on the nature of the discovery of

"Neurospora", which I believe can help illuminate the nature of scientfic progress

generally. The convergence of mutational genetics, biochemistry, nutrition
aid fungal-lifecycle-biology in fact contained no single ingredient that could
not be firmly predicted from preexisting knowldge -~ so what was the discovery?
Yet the focus of attention that was generated by the empirical demonstration

of Neurospora mutants transformed the biology of the generation.

Do you think the ARG would be an acceptable? a good vehicle for thas kind of
discussion?

Yours,

PLEASE ADDRESS COMMUNICATIONS IN CARE OF THE PRODUCTION EDITOR, ANNUAL REVIEW OF GENETICS, AT THE ABOVE ADDRESS.