March 3, 1955 Dr. Alan Garen Carnegie Institution of Washington Cold Spring Harbor, L.I., N.Y. Dear Alan: Thank you for your letter of the 29th. In one sense I was very pleased to see this, for the important reservation that I had had about your fellow- ship was just the point you brought up. If you were to come here, I would like to sount on a tenure of at least two years so that you could finish whatever work was started. On the other hand that would heve streéehed out your fellowship existence to 4-5 years, and that does seem grotesque. The other side of the coin was that I was beginning to anticipate some of the interesting things we might have been able to plen together. With the completion of the new Bacteriology Building here, we would have had access to various biophysical facilities, should ths need for them arise. All in all, however, I think you have made the wisest choioe, and I wish you the beat of luok on it. Should the situation change again, let me know. Your experiment sounis most ingenious— especially using phage to scavenge the DNA, It might even work! We shall probably still try to work ep the approach via singles cell isolation and autoradiography, though this sounds relatively unppomising, and there are a number of general technical probleus that have to be settled for this and some related experiments. With begt wishes, \\_ A, eaetber g i i .