525 EAST 68th STREET, NEW YORK. NY. 10021

THE NEW YORK HOSPITAL-CORNELL MEDICAL CENTER

DEPARTMENT OF PHARMACOLOGY (212) 472-6030
DEPARTMENT OF MEDICINE
DIVISION OF CLINICAL PHARMACOLOGY

     

     
    
 

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November 4, 1980

Joshua Lederberg, Ph.D.
President

Rockefeller University
NY, NY 10021

Dear Dr. Lederberg:

Thank you for the copy of the article from the Times on hydrazine
toxicity. I find it fascinating that, in addition to hydrazines being
present as industrial chemicals, fungi including the common edible mush-
room have phenylhydrazines present in amide linkage as a natural product.
The fungi also apparently contain the enzyme to hydrolize this amide
bond (Archives Biochem and Biophysics, 1979, 192:235-240; J Amer Chem
Soc 1961, 83:503-504). I appreciate your continued interest and encourage-
ment.

Best personal wishes.

Sincerely yours,

Marcus M. Reidenberg, M.D.
Professor of Pharmacology and Medicine
Head, Division of Clinical Pharmacology

MMR/jc