Prof. Ptashne [stamped, APR 2 1979] Thank you for your note (1) Hiroshima. There is no doubt of the sharp rise in leukemia. I said that the mutagenesis (though firmly predicted from other studies) could not be demonstrated in human populations (2) The most cautious and fair minded review of XYY is Witkin's: Science, 193:547 (1976) I don't think that "mental slowness" quite captures the behavior pattern. Nor, let it be said, does the "callous aggressiveness" that the media asserted. [END PAGE ONE] [BEGIN PAGE TWO] If there were less public fascination it might be possible to do the prospective studies needed to clear up the etiology; that seems out of the question now. Sincerely, Joshua. sams 170