MEMORIAL SLOAN-KETTERING CANCER CENTER 1275 YORK AVENUE, NEW YORK, NEW YORK 10021 (212) 879-3000 September 14, 1979 Dr. Henry Kunkel Rockefeller University York Ave. & East 66 Street New York, N.Y. 10021 Dear Henry: I just learned from Bob Good that his choice for the 1980 Philip Levine lecture is Hakomori. You will recall that in a recent telephone conversation we mentioned Hakomori and George Klein. We plan to invite Hakomori to meet with us regarding a new approach to investigate the biochemistry of breast cancer. It is now evident that Springer's 20 years work in this area - the T substance of Friedenreich and Thomsen and its relationship as precursors to N and M blood factors - has all been in vain. Enclosed is a copy of Blumenfeld's paper in PNAS, June 1978 on amino acids as determinants for M and N specificities. Also enclosed is a preprint of a paper soon to appear in a volume edited by Jamieson and Sandler. It is generally recognized that Hakomori's expertise in lipids and his notable contributions on the biochemistry of genetic markers of the ABO and Forssman antigens are essential for a study of breast adenocarcinoma. I hope that other members to be consulted will agree to Hakomori as the next Philip Levine lecturer possibly in the months of February or March 1980. We can consider George Klein for 1981 in view of his long experience on the possible role of viruses in cancer. Best regards. Sincerely yours, Philip Levine, M.D., er LO : Dr. Lederberg , . cor Or. tb ttn ry 7 VP RKELV OEY TS Exglih, oy Peel Vedey total 11 tits a-Y er Cf MEMORIAL HOSPITAL FOR CANCER AND ALLIED OISEASES . SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH SLOAN-KETTERING DIVISION, GRADUATE SCHOOL OF MEDICAL SCIENCES, CORNELL UNIVERSITY