CREFELLER Uivzy ge Ci V Cjpreruasn * (JAN 2% 1980 g & UE OF THe pees Mobil Oil Corporation ENVIRONMENTAL AFFAIRS AND TOXICOLOGY DEPARTMENT P.O. BOX 1026 PRINCETON, NEW JERSEY 08540 TELEPHONE (609) 452-9440 M.A. MEHLMAN DIRECTOR TOXICOLOGY DIVISION January 23, 1980 Joshua Lederberg, Ph.D. President The Rockefeller University 1230 York Avenue New York, New York 10021 Dear Dr. Lederberg: I have just spoken with Dr. Jim Withey of Canada. He will send us his chapter on "Pharmacokinetics and Toxicology" within two weeks. Just this morning, Professor Maltoni called from Italy. He has agreed to summarize all of his vinyl chloride data and the analogue data as well, on 6,000 animals with a complete tissue pathology with between 30 and 35 tissues per animal. This is probably the most comprehensive and complete carcinogenicity experiment that has ever been done. Professor Maltoni will also present a brief summary of this work in Washington on the 21st and 22nd of March at a meeting sponsored by NIEHS, OSHA, NIEHF, FDA and several other federal agencies. I will have this information after March 15th. This will be approximately 500 pages. Sincerely, “4. i an MAM: dls M. A. Mehlman cc: Barbara Mandula, Ph.D.